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Activation of central CRF receptor 1 by cortagine results in enhanced passive coping with a naturalistic threat in mice

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CRF receptor subtype 1 (CRF1), abundantly expressed in the central nervous system, has been implicated in defensive behavior in rodents. Pharmacological activation of CRF1 by peptidic agonists results in enhancement of anxiety-like behavior.



出版机构:Elsevier Science刊物名称:Psychoneuroendocrinology
出版时间:2010
ISSN:0306-4530
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