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Quantification of fipronil and its metabolite fipronil sulfone in rat plasma over a wide range of concentrations by LC/UV/MS

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Fipronil is an insecticide extensively used to treat pets, which has been identified as a potential thyroid disruptor in the rat. In this species, fipronil is mainly metabolized to fipronil sulfone and plasma concentrations of fipronil sulfone can be at least 20-fold higher than those of fipronil.



出版机构:Elsevier Science刊物名称:Journal of Chromatography B, Analytical Technologies in the Biomedical and
出版时间:2010
ISSN:1570-0232
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