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The use of EEG in Alzheimer’s disease, with and without scopolamine – A pilot study

To use multivariate statistical analysis of EEG data in order to separate EEGs of patients with Alzheimer?s disease (AD) from controls. A group of individuals with mild cognitive impairment (MCI) was evaluated using the same methodology.

出版机构:Elsevier Science

刊物名称:Clinical Neurophysiology

出版时间:2010

ISSN:1388-2457

数据源:报刊文摘

Live cell imaging of cytoskeletal dynamics in neurons using fluorescence photoactivation

Alzheimer's disease and other neurodegenerative disorders share some common features at the cellular level, which are often associated with a change in cytoskeletal dynamics. Live cell imaging has been applied to study various aspects of cell physiology including cytoskeletal dynamics.

出版机构:Walter de Gruyter

刊物名称:Biological Chemistry

出版时间:2010

ISSN:1437-4315

数据源:报刊文摘

Nicotine exacerbates tau phosphorylation and cognitive impairment induced by amyloid-beta 25–35 in rats

Nicotine was reported to reduce the plaque burden and could be used as a possible anti-Alzheimer's disease agent. However, the effect of nicotine on memory and tau pathology in Alzheimer's disease has been less studied.

出版机构:Elsevier Science

刊物名称:European Journal of Pharmacology

出版时间:2010

ISSN:0014-2999

数据源:报刊文摘

Detection of cytoplasmic PCK BB in nerve cell nuclei of normal, schizophrenic and alzheimer patients

Without Abstract

出版机构:Springer US

刊物名称:Bulletin of Experimental Biology and Medicine

出版时间:1993

ISSN:0007-4888

数据源:报刊文摘

Projecting independent components of SPECT images for computer aided diagnosis of Alzheimer’s disease

Finding sensitive and appropriate technologies for early detection of the Alzheimer?s disease (AD) are of fundamental importance to develop early treatments.

出版机构:Elsevier Science

刊物名称:Pattern Recognition Letters

出版时间:2010

ISSN:0167-8655

数据源:报刊文摘

Different implication of NEDD9 genetic variant in early and late-onset Alzheimer's disease

We analyzed the distribution of the rs760678 SNP polymorphism in 735 Italian subjects: 214 unrelated sporadic late-onset AD patients (LOAD, 64.5% females, mean age-at-onset 71.8?5.2 years), 135 early-onset AD patients (EOAD, 57.3% females, mean age-at-onset 57.5?5.

出版机构:Elsevier Science

刊物名称:Neuroscience Letters

出版时间:2010

ISSN:0304-3940

数据源:报刊文摘

Is modulation of nicotinic acetylcholine receptors by melatonin relevant for therapy with cholinergic drugs?

The daily variation of these complex processes is due to changes in specific mechanisms. In the last years we focused on the influence of melatonin on the expression and function of nicotinic acetylcholine receptors (nAChRs). Melatonin, either ?in vivo? or ?in vitro?

出版机构:Elsevier Science

刊物名称:Pharmacology & Therapeutics

出版时间:2010

ISSN:0163-7258

数据源:报刊文摘

Immunological Origin and Functional Properties of Catalytic Autoantibodies to Amyloid β Peptide

Objectives Objectives The objectives of this study are to (1) evaluate the ability of the immune system to synthesize specific antibodies that catalyze the degradation of amyloid ? peptide (A?

出版机构:Springer US

刊物名称:Journal of Clinical Immunology

出版时间:2010

ISSN:0271-9142

数据源:报刊文摘

Effects of trans-2,4-dimethoxystibene against the neurotoxicity induced by Aβ25–35 both in vitro and in vivo

Trans-2,4-dimethoxystibene (S3) is a synthetic stilbene. In this study, S3 was investigated in terms of its neuroprotective effect against the toxicity induced by ?-amyloid25?35 (A?25?35) both in vitro and in vivo.

出版机构:Elsevier Science

刊物名称:Neuroscience Research

出版时间:2010

ISSN:0168-0102

数据源:报刊文摘

Vascular risk factor detection and control may prevent Alzheimer's disease

The vascular hypothesis of Alzheimer disease (AD), first proposed by us in 1993, provides substantial evidence that suggests vascular risk factors (VRF) play a critical role in the development of cognitive decline and AD during aging.

出版机构:Elsevier Science

刊物名称:Ageing Research Reviews

出版时间:2010

ISSN:1568-1637

数据源:报刊文摘