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Cationic and anionic lipoplexes inhibit gene transfection by electroporation in vivo

Background Nonviral gene therapy still suffers from low efficiency. Methods that would lead to higher gene expression level of longer duration would be a major advance in this field. Lipidic vectors and physical methods have been investigated separately, and both induced gene expression improvement.

出版机构:John Wiley & Sons, Ltd.

刊物名称:The Journal of Gene Medicine

出版时间:2010

ISSN:1099-498X

数据源:报刊文摘

Real-time polymerase chain-reaction detection of pathogens is feasible to supplement the diagnostic sequence for urinary tract infections

The study included 301 prospectively collected urine samples from 189 patients with suspected UTI, based in a university hospital in 2005, and included outpatients and those in the ICU.

出版机构:Blackwell Publishing Ltd

刊物名称:BJU International

出版时间:2010

ISSN:1464-4096

数据源:报刊文摘

Mitochondrial DNA of the extinct quagga: Relatedness and extent of postmortem change

SummarySequences are reported for portions of two mitochondrial genes from a domestic horse and a plains zebra and compared to those published for a quagga and a mountain zebra.

出版机构:Springer Verlag

刊物名称:Journal of Molecular Evolution

出版时间:1987

ISSN:0022-2844

数据源:报刊文摘

Construction and analysis of an experimental Streptococcus iniae DNA vaccine

Streptococcus iniae is a severe aquaculture pathogen that can also infect humans and animal. A putative secretory antigen, Sia10, was identified from a pathogenic S. iniae strain by in vivo-induced antigen technology.

出版机构:Elsevier Science

刊物名称:Vaccine

出版时间:2010

ISSN:0264-410X

数据源:报刊文摘

Detection of eight frequently encountered point mutations in mitochondria in Chinese patients suggestive of mitochondrial encephalomyopathies

To evaluate eight frequently encountered mitochondrial DNA (mtDNA) point mutations (A3243G, T8993G/C, A8344G, A1555G, G11778A, G3460A and T14484C) in Chinese, we recruited 1559 sporadic patients suspected of mitochondrial diseases and 206 family members.

出版机构:Elsevier Science

刊物名称:Mitochondrion

出版时间:2010

ISSN:1567-7249

数据源:报刊文摘

The role of DNA membrane in the electro-oxidation methanol by nickel ions modified electrode in alkaline medium

DNA-Ni2+ complex film was prepared by using direct electrodeposited method. The nickel ions immobilized in the DNA membrane exhibited an excellent and stable catalytic activity to the electro-oxidation of methanol.

出版机构:Elsevier Science

刊物名称:Catalysis Communications

出版时间:2010

ISSN:1566-7367

数据源:报刊文摘

Connection between changes in membrane potential and DNA, RNA and protein synthesis in regenerating liver cells after partial hepatectomy

Without Abstract

出版机构:Springer US

刊物名称:Bulletin of Experimental Biology and Medicine

出版时间:1981

ISSN:0007-4888

数据源:报刊文摘

Analysis of functional consequences of haplogroup J polymorphisms m.4216T>C and m.3866T>C in human MT-ND1: Mutagenesis of homologous positions in Escherichia coli

MtDNA sequence variation is presumed to be neutral in effect, but associations with diseases and mtDNA haplogroups have been reported. The aim here was to evaluate the functional consequences of m.4216T>C present in haplogroup J. Furthermore, we evaluated m.

出版机构:Elsevier Science

刊物名称:Mitochondrion

出版时间:2010

ISSN:1567-7249

数据源:报刊文摘

Marked mitochondrial DNA depletion associated with a novel SUCLG1 gene mutation resulting in lethal neonatal acidosis, multi-organ failure, and interrupted aortic arch

A novel mutation in the SUCLG1 gene was identified. Phenotype severity in Succinate-CoA ligase dysfunction appears to be more correlated to the muscle mtDNA content than to the tissue distribution of the heterodimer subunits.

出版机构:Elsevier Science

刊物名称:Mitochondrion

出版时间:2010

ISSN:1567-7249

数据源:报刊文摘

Co-expression of Flt-3 ligand gene ablates tumor immunity elicited by HER-2/neu DNA vaccine in transgenic mice

Fms-like tyrosine-kinase 3 ligand (Flt-3L), is a powerful hematopoyetic growth factor, known to modulate the immune response against delivered antigens by acting either as an adjuvant or tolerogenic stimulus.

出版机构:Elsevier Science

刊物名称:Vaccine

出版时间:2010

ISSN:0264-410X

数据源:报刊文摘