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Development and validation of a HPLC method for the determination of sertraline and three non-chiral related impurities

The best results in terms of both retention time and resolution of the target analytes were obtained with a Zorbax Bonus-RP column, which contains a polar amide group embedded in a C14 alkyl chain.

出版机构:Elsevier Science

刊物名称:Journal of Pharmaceutical and Biomedical Analysis

出版时间:2010

ISSN:0731-7085

数据源:报刊文摘

Application of fully automated online solid phase extraction-liquid chromatography-electrospray-tandem mass spectrometry for the determination of sulfonamides and their acetylated metabolites in groundwater

The evaluation of the degree of SA pollution in groundwater was made through the analysis of a total of 39 samples taken in seven groundwater bodies of Catalonia (Spain). Recovery values obtained ranged from 34.

出版机构:Springer Verlag

刊物名称:Analytical and Bioanalytical Chemistry

出版时间:2011

ISSN:1618-2642

数据源:报刊文摘

Anthraquinones: Analytical Techniques as a Novel Tool to Investigate on the Triggering of Biological Targets

pproximately, 63% of marketed drugs derive from natural products or their semi synthetic derivatives. Compounds from living organisms often exert a biological activity, triggering several targets, which may be useful for the improvement of novel pharmaceuticals.

出版机构:Bentham Science Publishers

刊物名称:Current Drug Targets

出版时间:2011

ISSN:1389-4501

数据源:报刊文摘

Development and optimization of the SPE procedure for determination of pharmaceuticals in water samples by HPLC-diode array detection

This paper focuses on the investigation of different types of SPE sorbents for the preconcentration of eight veterinary pharmaceuticals from water samples.

出版机构:WILEY‐VCH Verlag

刊物名称:Journal of Separation Science

出版时间:2010

ISSN:1615-9306

数据源:报刊文摘

Development and Validation of Stability-Indicating HPLC Methods for Quantitative Determination of Pravastatin, Fluvastatin, Atorvastatin, and Rosuvastatin in Pharmaceuticals

High-performance liquid-chromatographic (HPLC) methods were validated for determination of pravastatin sodium (PS), fluvastatin sodium (FVS), atorvastatin calcium (ATC), and rosuvastatin calcium (RC) in pharmaceuticals.

出版机构:Taylor & Francis

刊物名称:Analytical Letters

出版时间:2009

ISSN:0003-2719

数据源:报刊文摘

Application of HILIC stationary phase to determination of dimethindene maleate in topical gel

novel high performance liquid chromatography method for the determination of dimethindene maleate in pharmaceutical gel using hydrophilic interaction liquid chromatography (HILIC) with UV detection was developed and validated.

出版机构:Elsevier Science

刊物名称:Journal of Pharmaceutical and Biomedical Analysis

出版时间:2009

ISSN:0731-7085

数据源:报刊文摘

HPLC Method for Simultaneous Determination of 1,4-Benzodiazepines and Tricyclic Antidepressants in Pharmaceutical Formulations and Saliva—A Useful Tool in Medicinal Chemistry

Herein, a sensitive and rapid reversed phase HPLC assay was developed for the simultaneous determination of 1,4-benzodiazepines and tricyclic antidepressants in human saliva and pharmaceutical formulations using colchicine as internal standard.

出版机构:Taylor & Francis

刊物名称:Journal of Liquid Chromatography & Related Technologies

出版时间:2009

ISSN:1082-6076

数据源:报刊文摘

Low biodegradability of fluoxetine HCl, diazepam and their human metabolites in sewage sludge-amended soil

Background, aim, and scope The European Union banned disposal of sewage sludge (SS) at sea in Europe in 1998. Since that time, the application rate of SS to land has risen significantly and is set to rise further.

出版机构:Springer Verlag

刊物名称:Journal of Soils and Sediments

出版时间:2008

ISSN:1439-0108

数据源:报刊文摘

Drug Dissolution Studies and Determination of Deflazacort in Pharmaceutical Formulations and Human Serum Samples by RP-HPLC

imple, sensitive, reproducible, and validated RP-HPLC method with UV detection is described for the determination of deflazacort in raw material, pharmaceuticals, human serum samples, and in-vitro drug dissolution studies. The separation was achieved using a C18 (250 ? 4.6 mm; 5 ?

出版机构:Taylor & Francis

刊物名称:Journal of Liquid Chromatography & Related Technologies

出版时间:2003

ISSN:1082-6076

数据源:报刊文摘

Simultaneous Determination of Fe(II) and Fe(III) in Pharmaceutical Samples by Post-Column Derivatization/HPLC

出版机构:Scientific and Technical Research Council of Turkey

刊物名称:Turkish Journal of Chemistry

出版时间:2002

ISSN:1300-0527

数据源:报刊文摘