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Development and validation of a HPLC method for determination of levonorgestrel and quinestrol in rat plasma

Levonorgestrel and quinestrol, commonly known as EP-1, has long been used in the control of wild rodents. Up to the present time, however, no method for simultaneous quantification of levonorgestrel and quinestrol in rat plasma has been reported.

出版机构:John Wiley & Sons, Ltd.

刊物名称:Biomedical Chromatography

出版时间:2010

ISSN:0269-3879

数据源:报刊文摘

HPLC method with fluorescence detection for the quantitative determination of flaxseed lignans

We report a rapid and simple HPLC method with fluorescence detection for the quantification of the major flaxseed lignan, secoisolarisiresinol diglucoside (SDG) and its major metabolites. The method is specific for SDG, secoisolarisiresinol (SECO), enterodiol (ED) and entrolactone (EL) in rat serum.

出版机构:Elsevier Science

刊物名称:Journal of Chromatography B, Analytical Technologies in the Biomedical and

出版时间:2010

ISSN:1570-0232

数据源:报刊文摘

A HPLC-UV method for the determination of puerarin in rat plasma after intravenous administration of PEGylated puerarin conjugate

ensitive and reproducible HPLC method for quantitative determination of puerarin (PUE) in rat plasma was developed and validated using 4-hydroxybenzaldehyde as an internal standard. The separation of PUE was performed on a CAPCELL PAK C18 column by gradient elution with 0.

出版机构:Elsevier Science

刊物名称:Journal of Chromatography B, Analytical Technologies in the Biomedical and

出版时间:2010

ISSN:1570-0232

数据源:报刊文摘

Bioactivities of water-soluble polysaccharides from Jisongrong mushroom: anti-breast carcinoma cell and antioxidant potential

Polysaccharides were extracted from Jisongrong mushroom. Jisongrong polysaccharides was a water-soluble compound. Its molecular weight was about 7.4?104 Da.

出版机构:Elsevier Science

刊物名称:International Journal of Biological Macromolecules

出版时间:2011

ISSN:0141-8130

数据源:报刊文摘

Quantification of fipronil and its metabolite fipronil sulfone in rat plasma over a wide range of concentrations by LC/UV/MS

Fipronil is an insecticide extensively used to treat pets, which has been identified as a potential thyroid disruptor in the rat. In this species, fipronil is mainly metabolized to fipronil sulfone and plasma concentrations of fipronil sulfone can be at least 20-fold higher than those of fipronil.

出版机构:Elsevier Science

刊物名称:Journal of Chromatography B, Analytical Technologies in the Biomedical and

出版时间:2010

ISSN:1570-0232

数据源:报刊文摘

A fast and sensitive HPLC–MS/MS analysis and preliminary pharmacokinetic characterization of cudratricusxanthone B in rats

method for the quantitative analysis of cudratricusxanthone B (CXB) in rat plasma by high performance liquid chromatography?electrospray ionization-tandem mass spectrometry (HPLC?ESI-MS/MS) has been developed and validated. The method involved liquid?

出版机构:Elsevier Science

刊物名称:Journal of Chromatography B, Analytical Technologies in the Biomedical and

出版时间:2010

ISSN:1570-0232

数据源:报刊文摘

Validated LC–MS (ESI) assay for the simultaneous determination of amitriptyline and its metabolite nortriptyline in rat plasma: Application to a pharmacokinetic comparison

pid, sensitive and specific method based on high performance liquid chromatography with electrospray ionization mass spectrometry (HPLC?MS/ESI) has been developed for the simultaneous determination of amitriptyline and nortriptyline in rat plasma. Sample preparation involved liquid?

出版机构:Elsevier Science

刊物名称:Journal of Pharmaceutical and Biomedical Analysis

出版时间:2010

ISSN:0731-7085

数据源:报刊文摘

Evaluation of the effects and mechanisms of action of glufosinate, an organophosphate insecticide, on striatal dopamine release by using in vivo microdialysis in freely moving rats

The purpose of the present work was to assess the effects of glufosinate ammonium (GLA), an aminoacid structurally related to glutamate, on in vivo dopamine (DA) release from rat striatum, using brain microdialysis coupled to HPLC-EC.

出版机构:Springer Verlag

刊物名称:Archives of Toxicology

出版时间:2010

ISSN:0340-5761

数据源:报刊文摘

Pharmacokinetics of kakkalide and its main metabolites in rat plasma determined by HPLC-DAD and LC–MS n

This study was undertaken to assess the plasma pharmacokinetic profile of kakkalide (KA), the major isoflavone found in extracts from the dried flower of Pueraria lobata.

出版机构:Elsevier Science

刊物名称:Journal of Chromatography B, Analytical Technologies in the Biomedical and

出版时间:2011

ISSN:1570-0232

数据源:报刊文摘

Purification and Partial Characterization of a New Pro-Inflammatory Lectin from Bauhinia bauhinioides Mart (Caesalpinoideae) Seeds

new galactose-specific lectin, named BBL, was purified from seeds of Bauhinia bauhinioides by precipitation with ammonium sulfate, followed by two steps of ion exchange chromatography.

出版机构:Bentham Science Publishers

刊物名称:Protein & Peptide Letters

出版时间:2011

ISSN:0929-8665

数据源:报刊文摘