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Simultaneous determination of pyrimethamine, sulfadoxine, mefloquine, and ibuprofen in pharmaceutical formulations by RP-HPLC

A simple and rapid high-performance liquid chromatographic (HPLC) method for simultaneous determination and quantification of pyramethamine, sulfadoxine, mefloquine HCl and ibuprofen was developed.

出版机构:Springer Verlag

刊物名称:Medicinal Chemistry Research

出版时间:2010

ISSN:1054-2523

数据源:报刊文摘

High-performance liquid chromatography assay of gnetol in rat serum and application to pre-clinical pharmacokinetic studies

method of analysis of gnetol (2,3?,5?,6-tetrahydroxy-trans-stilbene) in biological fluids is necessary for the study of its kinetics and disposition in plants.

出版机构:Elsevier Science

刊物名称:Journal of Pharmaceutical and Biomedical Analysis

出版时间:2011

ISSN:0731-7085

数据源:报刊文摘

Quantification of fipronil and its metabolite fipronil sulfone in rat plasma over a wide range of concentrations by LC/UV/MS

Fipronil is an insecticide extensively used to treat pets, which has been identified as a potential thyroid disruptor in the rat. In this species, fipronil is mainly metabolized to fipronil sulfone and plasma concentrations of fipronil sulfone can be at least 20-fold higher than those of fipronil.

出版机构:Elsevier Science

刊物名称:Journal of Chromatography B, Analytical Technologies in the Biomedical and

出版时间:2010

ISSN:1570-0232

数据源:报刊文摘

Identification, isolation, characterization and response factor determination of process-related impurity in meprobamate drug substance

This paper describes identification and characterization of a process-related impurity of meprobamate drug substance observed in HPLC-UV method. Forced degradation studies were carried out under acidic, basic, oxidation, light and thermal conditions to assess the nature of the impurity.

出版机构:Elsevier Science

刊物名称:Journal of Pharmaceutical and Biomedical Analysis

出版时间:2011

ISSN:0731-7085

数据源:报刊文摘

Application of HILIC stationary phase to determination of dimethindene maleate in topical gel

novel high performance liquid chromatography method for the determination of dimethindene maleate in pharmaceutical gel using hydrophilic interaction liquid chromatography (HILIC) with UV detection was developed and validated.

出版机构:Elsevier Science

刊物名称:Journal of Pharmaceutical and Biomedical Analysis

出版时间:2009

ISSN:0731-7085

数据源:报刊文摘

Simultaneous determination of five anthraquinones in medicinal plants and pharmaceutical preparations by HPLC with fluorescence detection

Chromatography was carried out at 25?C on a Hypersil C18 column with the isocratic mobile phase of methanol?0.1% aqueous formic acid (85:15, v/v) at a flow rate of 1.0ml/min. The excitation and emission wavelengths were set at 440 and 540nm, respectively.

出版机构:Elsevier Science

刊物名称:Journal of Pharmaceutical and Biomedical Analysis

出版时间:2009

ISSN:0731-7085

数据源:报刊文摘

Improved analytical validation and pharmacokinetics of valsartan using HPLC with UV detection

The primary objective of the study was to validate a simple and sensitive method of determining valsartan concentration in human plasma samples using high performance liquid chromatography (HPLC) combined with ultraviolet (UV) detection.

出版机构:Pharmaceutical Society of Korea

刊物名称:Archives of Pharmacal Research

出版时间:2008

ISSN:0253-6269

数据源:报刊文摘

Determination of Artemisinin in Artemisia annua L. by Reversed Phase HPLC

emisinin is a compound of current interest in the treatment of drug-resistant malaria. An accurate, sensitive, and reproducible reversed-phase HPLC with UV detection method is described for the determination of artemisinin in the herb of Artemisa annua L.

出版机构:Taylor & Francis

刊物名称:Journal of Liquid Chromatography & Related Technologies

出版时间:2005

ISSN:1082-6076

数据源:报刊文摘

An HPLC Determination of Trimetazidine in Human Plasma Using Liquid-Liquid Extraction for Sample Clean-Up

The method employs a liquid-liquid extraction for isolation and sample concentration, followed by reversed-phase liquid chromatography (RPLC) analysis using ultraviolet (UV) detection at 207 nm. Analytes were extracted from plasma samples that previously were mixed with 300 ?

出版机构:Taylor & Francis

刊物名称:Journal of Liquid Chromatography & Related Technologies

出版时间:2005

ISSN:1082-6076

数据源:报刊文摘

New RP-HPLC Method with UV-Detection for the Determination of Carvedilol in Human Serum

Carvedilol has been used as an antihypertensive drug and also possesses antioxidant and antiproliferative effects. A simple and sensitive analytical method for carvedilol in human serum by using high performance liquid chromatography (HPLC) was developed.

出版机构:Taylor & Francis

刊物名称:Journal of Liquid Chromatography & Related Technologies

出版时间:2007

ISSN:1082-6076

数据源:报刊文摘