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Total synthesis, purification, and characterization of human [Phe(p-CH2SO3Na)52, Nle32,53,56, Nal55]-CCK20–58, [Tyr52, Nle32,53,56,Nal55]-CCK-58, and [Phe(p-CH2SO3Na)52, Nle32,53,56, Nal55]-CCK-58

AbstractThe synthesis of [Phe(p-CH2SO3Na)52, Nle32,53,56 Nal55]-CCK20–58, [Tyr52, Nle32,53,56, Nal55]-CCK-58 and of [Phe(p-CH2SO3Na)52, Nle32,53,56, Nal55]-CCK-58 using the (9-fluorenylmethyloxy)-carbonyl (Fmoc) strategy on a 2,4-DMBHA resin is described.

出版机构:Kluwer Academic/Plenum Publishers

刊物名称:Journal of Protein Chemistry

出版时间:1993

ISSN:0277-8033

数据源:报刊文摘

Peptide Stability in Drug Development. II. Effect of Single Amino Acid Substitution and Glycosylation on Peptide Reactivity in Human Serum

AbstractThe determination of peptide stability in human serum (HS) or plasma constitutes a powerful screening assay for eliminating unstable peptides from further development. Herein we report on the stability in HS of several major histocompatibility complex (MHC)-binding peptides.

出版机构:Springer US

刊物名称:Pharmaceutical Research

出版时间:1993

ISSN:0724-8741

数据源:报刊文摘

Reappraisal of regional thiamine content in the central nervous system of the normal and thiamine-deficient mice

AbstractThe regional distribution of thiamine and its phosphate esters was measured in the central nervous system (CNS) of normal and thiamine-deficient mice.

出版机构:Springer US

刊物名称:Metabolic Brain Disease

出版时间:1993

ISSN:0885-7490

数据源:报刊文摘

Identification of metoclopramide metabolites in the urine of cattle by gas chromatography-mass spectrometry and high-performance liquid chromatography-photodiode array detection

The parent compound and one major metabolite (4-amino-5-chloro-N-[2-(ethylamino)ethyl]-2-methoxybenzamide) were common to all individuals.

出版机构:Springer Netherlands

刊物名称:Veterinary Research Communications

出版时间:1993

ISSN:0165-7380

数据源:报刊文摘

Kinetic Analysis of Molecular Interconversion of Immunosuppressant FK506 by High-Performance Liquid Chromatography

AbstractHigh-performance liquid chromatography of FK506, a macrolide immunosuppressant, was performed on a reversed-phase column. The peak was broad with the column kept at room temperature, which was accounted for by slow interconversion between the two forms of FK506.

出版机构:Springer US

刊物名称:Pharmaceutical Research

出版时间:1993

ISSN:0724-8741

数据源:报刊文摘

Does chlorophyllidea reduce reliability of chlorophylla measurements in marine coastal sediments?

Statistical analysis shows that the spectrophotometry with acidification, as compared to HPLC, gives reliable values for chlorophylla. Chlorophyllidea concentrations may be considered as negligible.

出版机构:SP Birkhäuser Verlag Basel

刊物名称:Aquatic Sciences

出版时间:1993

ISSN:1015-1621

数据源:报刊文摘

Selective Effect of Adjuvant Arthritis on the Disposition of Propranolol Enantiomers in Rats Detected Using a Stereospecific HPLC Assay

AbstractNonstereospecific studies have indicated that the pharmacokinetics of propranolol (PR) are altered in inflammatory conditions such as arthritis.

出版机构:Springer US

刊物名称:Pharmaceutical Research

出版时间:1993

ISSN:0724-8741

数据源:报刊文摘

Identification of the cytokinins in red pine seedlings

The basic fraction of both the roots and shoots contained zeatin, whereas the shoots contained dihydrozeatin-O-glucoside and the roots contained zeatin-O-glucoside.

出版机构:Springer Netherlands

刊物名称:Plant Growth Regulation

出版时间:1993

ISSN:0167-6903

数据源:报刊文摘

High performance liquid chromatography of the ketimine forms of aminoethylcysteine, lanthionine and cystathionine after precolumn derivatization with 2,4-dinitrophenylhydrazine

AbstractThe cyclic ketimines derived from the monodeamination of aminoethylcysteine, lanthionine and cystathionine in HCl solution are open and react with carbonyl reagents.

出版机构:Springer Verlag

刊物名称:RENDICONTI LINCEI

出版时间:1993

ISSN:1120-6349

数据源:报刊文摘

Single-Puff Particle-Size Analysis of Albuterol Metered-Dose Inhalers (MDIs) by High-Pressure Liquid Chromatography with Electrochemical Detection (HPLC-EC)

Without Abstract

出版机构:Springer US

刊物名称:Pharmaceutical Research

出版时间:1993

ISSN:0724-8741

数据源:报刊文摘