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Tonsillar diffusion kinetics of amoxycillin after oral administration of 1 g to adults

Summary Although amoxycillin is widely used to treat pharyngo-tonsillitis, the kinetics of tonsillar diffusion have rarely been studied. The aim of this work was to study the kinetics of amoxycillin diffusion in the tonsils of adults, by measuring tonsillar concentrations 1.

出版机构:Springer Verlag

刊物名称:European Journal of Drug Metabolism and Pharmacokinetics

出版时间:1997

ISSN:0378-7966

数据源:报刊文摘

Metabolism of mangafodipir trisodium (MnDPDP), a new contrast medium for magnetic resonance imaging, in beagle dogs

In the low-dose group, the parent compound MnDPDP was present at the lowest concentration compared to the metabolites at the first sampling time point, 1 min after the end of infusion, whereas MnPLED was the main metabolite. At 30 min post-infusion ZnPLED was the main metabolite.

出版机构:Springer Verlag

刊物名称:European Journal of Drug Metabolism and Pharmacokinetics

出版时间:1997

ISSN:0378-7966

数据源:报刊文摘

An improved HPLC method for analysis of methamphetamine and its metabolites in plasma

The major modification on the previous extraction procedure is addition of HCl to ethyl acetate extract prior to evaporation, resulting in significant increases in recovery, reproducibility and sensitivity.

出版机构:Springer Verlag

刊物名称:European Journal of Drug Metabolism and Pharmacokinetics

出版时间:1997

ISSN:0378-7966

数据源:报刊文摘

Standardization of marker assays - pyridinoline/deoxypyridinoline

The hydroxypyridinium collagen crosslinks pyridinoline and deoxypyridinoline (Dpd) are released during the degradation of some mature collagens. Assays for the peptide forms of these crosslinks in blood and urine and for the free and total crosslinks in urine have been developed.

出版机构:Informa Healthcare

刊物名称:Scandinavian Journal of Clinical and Laboratory Investigation

出版时间:1997

ISSN:0036-5513

数据源:报刊文摘

Some Considerations Regarding the Use of Amino Acid Racemization in Human Dentine as an Indicator of Age at Death

An HPLC method is described for simultaneously obtaining the enantiomeric ratio of three amino acids (aspartic acid, serine, and glutamic acid) from dental collagen, with a view to using this information for estimating age at death.

出版机构:Blackwell Publishing Ltd

刊物名称:Journal of Forensic Sciences

出版时间:1997

ISSN:0022-1198

数据源:报刊文摘

HPLC/MS Determination of Buprenorphine and Norbuprenorphine in Biological Fluids and Hair Samples

An original method, based upon HPLC (high performance liquid chromatography)/Ionspray-MS, has been developed for the identification of buprenorphine (BUP) and norbuprenorphine (norBUP) in biological fluids and hair samples. Biological fluids (2 mL) are extracted at pH 8.

出版机构:Blackwell Publishing Ltd

刊物名称:Journal of Forensic Sciences

出版时间:1997

ISSN:0022-1198

数据源:报刊文摘

Simultaneous Determination of Cephalexin and Carbocisteine from Capsules by Reverse Phase High Performance Liquid Chromatography (RP - HPLC).

new, simple, precise, accurate and rapid RP- HPLC method has been developed for the simultaneous determination of Cephalexin and Carbocisteine from capsules, using 0.025 M monobasic sodium phosphate: acetonitrile (87:13, v/v) as a mobile phase, and a C8 Shodex column as the stationary phase.

出版机构:Taylor & Francis

刊物名称:Analytical Letters

出版时间:1997

ISSN:0003-2719

数据源:报刊文摘

Simultaneuous Determination of Enalpril Maleate and Hydrochlorothiazide in Tablets by Reversed Phase HPLC

new simple, precise, rapid and selective RP-HPLC method has been developed for the simultaneous determination of Enalpril maleate and Hydrochlorothiazide from formulations, using 0.025M orthophosphoric acid [(adjusted to pH 3.

出版机构:Taylor & Francis

刊物名称:Analytical Letters

出版时间:1997

ISSN:0003-2719

数据源:报刊文摘

Resolution Optimization in Ion-Interaction RP-HPLC.

Since in ion-interaction chromatography the dependence of the retention on the concentration of the ion-interaction reagent (IIR) follows different behaviours for the different analytes, the adjustment of IIR concentration can usefully be used to optimize resolution.

出版机构:Taylor & Francis

刊物名称:Analytical Letters

出版时间:1997

ISSN:0003-2719

数据源:报刊文摘

Multi-Residue Analysis of Frequently Applied Herbicides from Soil Samples Taken in the Area of Halle/S. (FRG)

high-resolution multimethod is presented for simultaneous determination of frequently applied s-triazine and phenoxyalkanoic acid herbicides extracted from soil samples.

出版机构:Taylor & Francis

刊物名称:International Journal of Environmental & Analytical Chemistry

出版时间:1997

ISSN:0306-7319

数据源:报刊文摘