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Comparative bioavailability study of codeine and ibuprofen after administration of the two products alone or in association to 24 healthy volunteers

Summary The study objective was to compare the bioavailability of codeine and ibuprofen after oral administration of the two drugs alone or in association. The study was performed in three different periods, each separated by a wash-out of 6 days.

出版机构:Springer Verlag

刊物名称:European Journal of Drug Metabolism and Pharmacokinetics

出版时间:1998

ISSN:0378-7966

数据源:报刊文摘

Acetaminophen presystemic biotransformation vs bioavailability in therapeutical dosage range

Summary The influence of dose on the absorption and presystemic biotransformation of acetaminophen was studied in 15 healthy volunteers after administration of 3 different oral doses (250 mg, 500 mg, 750 mg) following a 3?3 Latin Square Design.

出版机构:Springer Verlag

刊物名称:European Journal of Drug Metabolism and Pharmacokinetics

出版时间:1998

ISSN:0378-7966

数据源:报刊文摘

Studies on Speciation of Antimony in Soil Contaminated by Industrial Activity

ntimony is a toxic trace element of growing environmental interest due to its increased anthropogenic input into the environment. Very little is known about the chemical and biological behavior of antimony compounds in soils and sediments.

出版机构:Taylor & Francis

刊物名称:International Journal of Environmental & Analytical Chemistry

出版时间:1998

ISSN:0306-7319

数据源:报刊文摘

Analysis of linear alkylbenzenesulfonates in sediments from the Bolmon pond (France) by high-performance liquid chromatography

Linear alkylbenzenesulfonates (LASs) concentrations were determined in the sediments from an European pond (the Bolmon pond, France), by high-performance liquid chromatography (HPLC), after extraction of samples with C18 mini-column cartridges. The levels of total LASs ranged from 0.5 to 6.0 ?

出版机构:Taylor & Francis

刊物名称:Toxicological and Environmental Chemistry

出版时间:1998

ISSN:0277-2248

数据源:报刊文摘

Lignan Glycosides from Trichilia estipulata Bark

The methanol extract of the stem bark of Trichilia estipulata afforded four aryltetralin lignan glycosides which were identified on the basis of spectroscopic analysis of their acetates as (-)-isolariciresinol-3?-O-?-D-xylopyranoside and the new lignans (+)-4'-0-methyl-9'-deoxiisolariciresinol-3?

出版机构:Taylor & Francis

刊物名称:Natural Product Research

出版时间:1998

ISSN:1478-6419

数据源:报刊文摘

Validation of Cleaning Procedures for Highly Potent Drugs. II. Bisnafide

The objective of this work was the development and validation of procedures designed to clean glass and stainless steel surfaces after exposure to the experimental anticancer drug, bisnajide. The cleaning procedures, using 5% acetic acid water, Alconox?

出版机构:Informa Healthcare

刊物名称:Pharm Dev Technol

出版时间:1998

ISSN:1083-7450

数据源:报刊文摘

Specific Determination of PAH and Its N-Acetyl Metabolite by HPLC Increases the Accuracy and Precision of PAH Clearance Measurements

PAH (N-(4-aminohenzovl)-glycin) clearance measurements have been used for 50 years in clinical research for the determination of renal plasma flow. The quantitation of PAH in plasma or urine is generally performed by colorimetric method after diazotation reaction.

出版机构:Informa Healthcare

刊物名称:Ren Fail

出版时间:1998

ISSN:0886-022X

数据源:报刊文摘

A systematic study on the stability of selected polymer antioxidants in EU official aqueous and alternative food simulants using HPLC

Whilst considerable research has been conducted on the stability of plastics additives during processing, there is, on the other hand, a lack of studies on the stability of the same additives in food simulants in the published literature.

出版机构:Taylor & Francis

刊物名称:Food Additives & Contaminants

出版时间:1998

ISSN:0265-203X

数据源:报刊文摘

Application of liquid chromatography-atmospheric pressure chemical ionization mass spectrometry and tandem mass spectrometry to the determination of volatile nitrosamines in dry sausages

high-performance liquid chromatographic-atmospheric pressure chemical ionization mass spectrometric method was developed for the determination of volatile nitrosamines in dry sausages.

出版机构:Taylor & Francis

刊物名称:Food Additives & Contaminants

出版时间:1998

ISSN:0265-203X

数据源:报刊文摘

Anthocyanins from flowers of Crocus (iridaceae)

出版机构:Elsevier Science

刊物名称:Phytochemistry

出版时间:1998

ISSN:0031-9422

数据源:报刊文摘