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While both gray and white matters were examined, significant CBV deficit regions were primarily located in white matter, specifically in frontal and parietal lobes, in which CBV was reduced by 20% in the AD/MCI group. 出版机构:Elsevier Science 刊物名称:Neurobiology of Aging 出版时间:2010 ISSN:0197-4580 数据源:报刊文摘
Objective To describe the AddNeuroMed imaging framework for multi?centre magnetic resonance imaging (MRI) assessment of longitudinal changes in Alzheimer's disease and report on early results from the first 24 months of the project.
出版机构:John Wiley & Sons, Ltd. 刊物名称:International Journal of Geriatric Psychiatry 出版时间:2011 ISSN:0885-6230 数据源:报刊文摘
出版机构:Elsevier Science
刊物名称:Journal of Biotechnology
出版时间:2010
ISSN:0168-1656
数据源:报刊文摘
We determined predictors of conversion to Alzheimer?s disease (AD) from mild cognitive impairment (MCI) with automated magnetic resonance imaging (MRI) regional cortical volume and thickness measures. 出版机构:Elsevier Science 刊物名称:Neurobiology of Aging 出版时间:2010 ISSN:0197-4580 数据源:报刊文摘
ophic changes in early Alzheimer's disease (AD) and amnestic mild cognitive impairment (MCI) have been proposed as biomarkers for detection and monitoring. 出版机构:Elsevier Science 刊物名称:Neurobiology of Aging 出版时间:2010 ISSN:0197-4580 数据源:报刊文摘
We set out to determine factors that influence the rate of brain atrophy in 1-year longitudinal magnetic resonance imaging (MRI) data. With tensor-based morphometry (TBM), we mapped the 3-dimensional profile of progressive atrophy in 144 subjects with probable Alzheimer's disease (AD) (age: 76.5 ? 出版机构:Elsevier Science 刊物名称:Neurobiology of Aging 出版时间:2010 ISSN:0197-4580 数据源:报刊文摘
People with the apolipoprotein-E?4 (APOE-4) genetic risk for Alzheimer's disease show morphologic differences in medial temporal lobe regions when compared to non-carriers of the allele. 出版机构:Elsevier Science 刊物名称:NeuroImage 出版时间:2010 ISSN:1053-8119 数据源:报刊文摘
For both clinical and research reasons, it is essential to identify which mild cognitive impairment (MCI) subjects subsequently progress to Alzheimer?s disease (AD). The prediction may be facilitated by accelerated whole brain atrophy exhibited by AD subjects. 出版机构:Elsevier Science 刊物名称:Neurobiology of Aging 出版时间:2010 ISSN:0197-4580 数据源:报刊文摘
To develop an automated imaging assessment tool that accommodates the anatomic variability of the elderly and demented population as well as the registration errors occurring during spatial normalization. 出版机构:Elsevier Science 刊物名称:NeuroImage 出版时间:2005 ISSN:1053-8119 数据源:报刊文摘
Effective and accurate diagnosis of Alzheimer's disease (AD), as well as its prodromal stage (i.e., mild cognitive impairment (MCI)), has attracted more and more attention recently. So far, multiple biomarkers have been shown to be sensitive to the diagnosis of AD and MCI, i.e. 出版机构:Elsevier Science 刊物名称:NeuroImage 出版时间:2011 ISSN:1053-8119 数据源:报刊文摘
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