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Multiple sclerosis lesions: insights from imaging techniques

The hallmark of multiple sclerosis (MS) pathology is the presence of inflammatory demyelinated lesions distributed throughout the CNS. Along with more diffuse tissue abnormalities, it is considered one of the major determinants of neurological deficit in MS.

出版机构:Expert Reviews Ltd

刊物名称:ern

出版时间:2009

ISSN:1473-7175

数据源:报刊文摘

Characterization of brain lesions in a mouse model of progressive multiple sclerosis

Multiple sclerosis (MS) is an autoimmune disease of the central nervous system characterized by damage to the neuronal myelin sheath, which results in different levels of muscle paralysis that can lead to neuronal death.

出版机构:Elsevier Science

刊物名称:Experimental Neurology

出版时间:2010

ISSN:0014-4886

数据源:报刊文摘

Spinal cord involvement in multiple sclerosis: A correlative MRI and high-resolution HLA-DRB1 genotyping study

There have been few magnetic resonance imaging (MRI) studies of the spinal cord in large multiple sclerosis (MS) patient cohorts and little is known about correlations between cord lesions and human leukocyte antigen (HLA) alleles.

出版机构:Elsevier Science

刊物名称:Journal of the Neurological Sciences

出版时间:2011

ISSN:0022-510X

数据源:报刊文摘

Structural integrity of callosal midbody influences intermanual transfer in a motor reaction‐time task

Training one hand on a motor task results in performance improvements in the other hand, also when stimuli are randomly presented (nonspecific transfer).

出版机构:Wiley Subscription Services, Inc., A Wiley Company

刊物名称:Human Brain Mapping

出版时间:2011

ISSN:1065-9471

数据源:报刊文摘

Diagnostic problems in “clinically definite” multiple sclerosis patients with normal CSF and multiple MRI abnormalities

Alternative diagnoses reached after laboratory tests were: Lyme disease, two cases of vasculitis, mitochondrial encephalomyopathy, multiple ischemic lesions caused by atrial septum aneurysm and olivopontocerebellar atrophy.

出版机构:Blackwell Publishing Ltd

刊物名称:European Journal of Neurology

出版时间:1994

ISSN:1351-5101

数据源:报刊文摘

Everyday memory impairment, neuroradiological findings and physical disability in multiple sclerosis

Thirty?five multiple sclerosis (MS) patients diagnosed according to the Poser criteria were examined in a variety of cognition and memory tasks. Their performance was compared to age? and gender?matched healthy individuals. While there was no difference in overall intellectual performance and short?

出版机构:Blackwell Publishing Ltd

刊物名称:European Journal of Neurology

出版时间:1994

ISSN:1351-5101

数据源:报刊文摘

Monoballism revealing multiple sclerosis. Neuroradiological aspects

38?year?old woman suddenly showed signs of monoballism in the right upper limb. Examination of CSF showed 13 monocytes per mm3 and 28.7% of IgG in oligoclonal bands. MRI examination showed several high signal lesions in T2?

出版机构:Blackwell Publishing Ltd

刊物名称:European Journal of Neurology

出版时间:1996

ISSN:1351-5101

数据源:报刊文摘

Metabolism and regional cerebral blood volume in autoimmune inflammatory demyelinating lesions mimicking malignant gliomas

Dynamic susceptibility contrast (DSC) magnetic resonance imaging (MRI) and MR spectroscopy are thought to differentiate tumefactive autoimmune inflammatory demyelinating lesions from glial brain tumours.

出版机构:Springer Verlag

刊物名称:Journal of Neurology

出版时间:2011

ISSN:0340-5354

数据源:报刊文摘

A prospective study of “undiagnosed” isolated myelopathy: II. Value of magnetic resonance imaging, evoked potentials and CSF analysis

We aimed to determine the sensitivity of available ?diagnostic? tests in detecting subclinical abnormalities characteristic of multiple sclerosis (MS) in patients with unexplained isolated myelopathy, and any relationship between test results and level of disability.

出版机构:Blackwell Publishing Ltd

刊物名称:European Journal of Neurology

出版时间:1995

ISSN:1351-5101

数据源:报刊文摘

Natural interferon‐beta in chronic progressive multiple sclerosis: results after 2 years of treatment and 2 years of follow up

Seventeen chronic progressive multiple sclerosis patients were treated with natural interferon?beta (IFN??) for 2 years, thereafter they were followed up for 2 years. IFN?? was given 1 million IU/day i.m.

出版机构:Blackwell Publishing Ltd

刊物名称:European Journal of Neurology

出版时间:1995

ISSN:1351-5101

数据源:报刊文摘