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Oxidative modifications in glycated insulin

At the present, the term glycoxidation is recognized as the synergistic interaction between glycation and oxidative processes which, with the help of redox-active metals, consequently leads to the production of deleterious tissue modifications.

出版机构:Springer Verlag

刊物名称:Analytical and Bioanalytical Chemistry

出版时间:2010

ISSN:1618-2642

数据源:报刊文摘

Quantification of urinary 8-iso-prostaglandin F2α using liquid chromatography-tandem mass spectrometry during cardiac valve surgery

Oxidative stress is an unavoidable event during many complex surgical procedures. 8-iso-prostaglandin F2? (8-iso-PGF2?) is a reliable biomarker for the evaluation of oxidative stress in vivo.

出版机构:Wiley Subscription Services, Inc., A Wiley Company

刊物名称:Journal of Clinical Laboratory Analysis

出版时间:2010

ISSN:0887-8013

数据源:报刊文摘

Corticotropin-releasing factor-2 activation prevents gentamicin-induced oxidative stress in cells derived from the inner ear

Generation of reactive oxygen species (ROS) is a common denominator in many conditions leading to cell death in the cochlea, yet little is known of the cochlea's endogenous mechanisms involved in preventing oxidative stress and its consequences in the cochlea.

出版机构:Wiley Subscription Services, Inc., A Wiley Company

刊物名称:Journal of Neuroscience Research

出版时间:2010

ISSN:0360-4012

数据源:报刊文摘

Advances in methods for the determination of biologically relevant lipid peroxidation products

This article gives an overview of the most currently used methods and then addresses the recent advances in some specific approaches.

出版机构:Informa Healthcare

刊物名称:Free Radical Research

出版时间:2010

ISSN:1071-5762

数据源:报刊文摘

Targeted label-free quantitative analysis of secretory proteins from adipocytes in response to oxidative stress

dipocytes are well known to release regulation factors associated with metabolic disorders. In particular, increased oxidative stress in adipocytes contributes to dysregulation of adipokine production.

出版机构:Elsevier Science

刊物名称:Analytical Biochemistry

出版时间:2010

ISSN:0003-2697

数据源:报刊文摘

Relative contribution of DNA strand breaks and DNA adducts to the genotoxicity of benzo[a]pyrene as a pure compound and in complex mixtures

A comparison was made between the extent of DNA strand breaks as determined by the Comet assay and the number of DNA adducts to the diol epoxide metabolite of B[a]P measured by HPLC?mass spectrometry.

出版机构:Elsevier Science

刊物名称:Mutation Research

出版时间:2009

ISSN:0027-5107

数据源:报刊文摘

New techniques to detect oxidative stress markers: Mass spectrometry-based methods to detect isoprostanes as the gold standard for oxidative stress in vivo

Free radical-induced lipid oxidation under oxidative stress has been implicated in a number of human diseases. Isoprostanes (IsoPs), isomers of prostaglandins, are one of the major classes of oxidation products derived from this oxidation process.

出版机构:Wiley Subscription Services, Inc., A Wiley Company

刊物名称:BioFactors

出版时间:2008

ISSN:0951-6433

数据源:报刊文摘

Lysophosphatidylethanolamine is – in contrast to – choline – generated under in vivo conditions exclusively by phospholipase A2 but not by hypochlorous acid

Inflammatory liver diseases are associated with oxidative stress mediated particularly by neutrophilic granulocytes. At inflammatory loci, hypochlorous acid (HOCl) is generated by myeloperoxidase.

出版机构:Elsevier Science

刊物名称:Bioorganic Chemistry

出版时间:2009

ISSN:0045-2068

数据源:报刊文摘

Isolevuglandins covalently modify phosphatidylethanolamines in vivo: Detection and quantitative analysis of hydroxylactam adducts

Levuglandins (LGs) and isolevuglandins (isoLGs, also called ?isoketals? or ?isoKs?) are extraordinarily reactive products of cyclooxygenase- and free radical-induced oxidation of arachidonates.

出版机构:Elsevier Science

刊物名称:Free Radical Biology and Medicine

出版时间:2009

ISSN:0891-5849

数据源:报刊文摘

The Sod2 mutant mouse as a model for oxidative stress: A functional proteomics perspective

To fully appreciate the widespread molecular consequences under increased oxidative stress, a systems approach utilizing proteomics is able to provide a global overview of the complex biological changes, which a targeted single biomolecular approach cannot address fully.

出版机构:Wiley Subscription Services, Inc., A Wiley Company

刊物名称:Mass Spectrometry Reviews

出版时间:2010

ISSN:0277-7037

数据源:报刊文摘