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Hb J-CAPE TOWN [αα92(FG4)Arg→→Gln (αα1), CGG→→CAG] in Southern Italy Found in a Patient with Erythrocytosis

high oxygen affinity hemoglobin (Hb) variant, Hb J-Cape Town [??92(FG4)Arg??Gln (??1), CGG??CAG] was identified in a 30-year-old woman patient from Cosenza (Southern Italy) who had previously been diagnosed with juvenile polycythemia in other hospitals.

出版机构:Informa Healthcare

刊物名称:Hemoglobin

出版时间:2007

ISSN:0363-0269

数据源:报刊文摘

Proteomic Methods for Biomarker Discovery in Urine

Yet despite these difficulties, substantial progress has been achieved with the application of proteomic methods toward biomarker discovery in renal disease.

出版机构:Elsevier Science

刊物名称:Seminars in Nephrology

出版时间:2007

ISSN:0270-9295

数据源:报刊文摘

Direct Tissue Analysis by Matrix-Assisted Laser Desorption Ionization Mass Spectrometry: Application to Kidney Biology

Direct tissue analysis using matrix-assisted laser desorption ionization mass spectrometry (MALDI MS) provides in situ molecular analysis of a wide variety of biological molecules including xenobiotics.

出版机构:Elsevier Science

刊物名称:Seminars in Nephrology

出版时间:2007

ISSN:0270-9295

数据源:报刊文摘

Proteomics as a tool for biomarker discovery

Despite these critical descriptors, the few available FDA-approved biomarkers for cancer do not completely fit this definition and their benefits are limited to a small number of cancers.

出版机构:IOS Press

刊物名称:Disease Markers

出版时间:2007

ISSN:0278-0240

数据源:报刊文摘

Biomarker discovery with SELDI-TOF MS in human urine associated with early renal injury: evaluation with computational analytical tools

Background. Urine proteomics is one of the key emerging technologies to discover new biomarkers for renal disease, which may be used in the early diagnosis, prognosis and treatment of patients.

出版机构:Oxford University Press

刊物名称:Nephrology Dialysis Transplantation

出版时间:2007

ISSN:0931-0509

数据源:报刊文摘

Characterization of glycoinositolphosphoryl ceramide structure mutant strains of Cryptococcus neoformans

As an effort to understand the biosynthesis of these sphingolipids, we have now characterized the structures of GIPCs from C. neoformans wild-type (KN99?

出版机构:Oxford University Press

刊物名称:Glycobiology

出版时间:2007

ISSN:0959-6658

数据源:报刊文摘

Comparison of the methods for profiling glycoprotein glycans—HUPO Human Disease Glycomics/Proteome Initiative multi-institutional study

Mass spectrometry (MS) of glycoproteins is an emerging field in proteomics, poised to meet the technical demand for elucidation of the structural complexity and functions of the oligosaccharide components of molecules.

出版机构:Oxford University Press

刊物名称:Glycobiology

出版时间:2007

ISSN:0959-6658

数据源:报刊文摘

Integrated mass spectrometric strategy for characterizing the glycans from glycosphingolipids and glycoproteins: direct identification of sialyl Lex in mice

The current interest in applying systems biology approaches to studying an organism's form or function promises to reveal further insights into the role of glycosylation in cells and whole organisms.

出版机构:Oxford University Press

刊物名称:Glycobiology

出版时间:2007

ISSN:0959-6658

数据源:报刊文摘

Affinities of Shiga toxins 1 and 2 for univalent and oligovalent Pk-trisaccharide analogs measured by electrospray ionization mass spectrometry

The binding stoichiometry and affinities of the Shiga toxins, Stx1 and Stx2, for a series of uni- and oligovalent analogs of the Pk-trisaccharide were measured using the direct electrospray ionization mass spectrometry (ES-MS) assay.

出版机构:Oxford University Press

刊物名称:Glycobiology

出版时间:2007

ISSN:0959-6658

数据源:报刊文摘

Characterization of neutral and acidic glycosphingolipids from the lectin-producing mushroom, Polyporus squamosus

In considering the possibility that the lectin's in vivo function could involve interaction with an endogenous glycoconjugate, it would clearly be helpful to identify candidate ligands among various classes of carbohydrate-containing materials expressed by P. squamosus.

出版机构:Oxford University Press

刊物名称:Glycobiology

出版时间:2007

ISSN:0959-6658

数据源:报刊文摘