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Hyperpolarization-activated ion channels as targets for nitric oxide signalling in deep cerebellar nuclei

Abstract

Most biological effects of nitric oxide (NO) in the brain are mediated by guanylyl cyclase-coupled NO receptors, whose activation results in increased intracellular cGMP levels.

出版机构:Blackwell Publishing Ltd

刊物名称:European Journal of Neuroscience

出版时间:2010

ISSN:0953-816X

数据源:报刊文摘

Neonatal Handling Impairs Spatial Memory and Leads to Altered Nitric Oxide Production and DNA Breaks in A Sex Specific Manner

Litters of rats were non-handled or handled (10 min/day, days 1?10 after birth). In adulthood they were subjected to a Morris water maze or used for biochemical evaluations. Female handled rats showed impairment in spatial learning.

出版机构:Springer US

刊物名称:Neurochemical Research

出版时间:2010

ISSN:0364-3190

数据源:报刊文摘

Validity of Measurement of Two Specific Biomarkers for the Assessment of Small Airways Inflammation in Asthma

Methods: The authors measured CML levels in induced sputum and the bronchial flux (Jno) and alveolar concentration (Calv) of NO in 37 asthmatic patients and 15 normal controls.

出版机构:Informa Healthcare

刊物名称:J Asthma

出版时间:2010

ISSN:0277-0903

数据源:报刊文摘

High-dose antithrombin III prevents heat stroke by attenuating systemic inflammation in rats

Objective Systemic inflammatory mediators, including the high mobility group box 1 (HMGB1) protein, play important roles in the development of various inflammatory conditions.

出版机构:SP Birkhäuser Verlag Basel

刊物名称:Inflammation Research

出版时间:2010

ISSN:1023-3830

数据源:报刊文摘

Multiple protective functions of catalase against intercellular apoptosis-inducing ROS signaling of human tumor cells

Tumor cells are protected against intercellular reactive oxygen species (ROS)-mediated apoptosis signaling mediated by the HOCl and/or the nitric oxide (NO)/peroxynitrite signaling pathway.

出版机构:Walter de Gruyter

刊物名称:Biological Chemistry

出版时间:2010

ISSN:1437-4315

数据源:报刊文摘

Alterations of interneurons in the striatum and frontal cortex of mice during postnatal development

We investigated the postnatal alterations of neuronal nuclei (NeuN)-positive neurons, parvalbumin (PV)-positive interneurons, neuronal nitric oxide synthase (nNOS)-positive interneurons, and neurotrophic factors in the mouse striatum and frontal cortex using immunohistochemistry.

出版机构:Elsevier Science

刊物名称:International Journal of Developmental Neuroscience

出版时间:2010

ISSN:0736-5748

数据源:报刊文摘

The effect of sildenafil on sleep respiratory parameters and heart rate variability in obstructive sleep apnea

To evaluate the magnitude of effects of sildenafil on respiratory parameters and heart rate variability (HRV) in slow wave sleep (SWS) and REM sleep of patients with severe obstructive sleep apnea (OSA).

出版机构:Elsevier Science

刊物名称:Sleep Medicine

出版时间:2010

ISSN:1389-9457

数据源:报刊文摘

Curcumin protects pre-oligodendrocytes from activated microglia in vitro and in vivo

Infection and inflammation leading to injury or death of pre-oligodendrocytes (preOLs) is one of the principal initiating mechanisms in the pathogenesis of preterm periventricular leukomalacia (PVL).

出版机构:Elsevier Science

刊物名称:Brain Research

出版时间:2010

ISSN:0006-8993

数据源:报刊文摘

Tetramethylpyrazine inhibits production of nitric oxide and inducible nitric oxide synthase in lipopolysaccharide-induced N9 microglial cells through blockade of MAPK and PI3K/Akt signaling pathways, and suppression of intracellular reactive oxygen species

To determine the inhibitory effect of tetramethylpyrazine (TMP) on lipopolysaccharide (LPS)-induced over-production of nitric oxide (NO) and inducible nitric oxide synthase (iNOS) in N9 microglial cells.

出版机构:Elsevier Science

刊物名称:Journal of Ethnopharmacology

出版时间:2010

ISSN:0378-8741

数据源:报刊文摘