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A novel CYP2A6*20 allele found in African-American population produces a truncated protein lacking enzymatic activity

Human CYP2A6 is a cytochrome P450 (CYP) isoform responsible for the metabolism of nicotine, coumarin, tegafur, and valproic acid, and metabolic activation of nitrosamines.

出版机构:Elsevier Science

刊物名称:Biochemical Pharmacology

出版时间:2005

ISSN:0006-2952

数据源:报刊文摘

Nicotine self-administration in mice is associated with rates of nicotine inactivation by CYP2A5

Rationale Cyp2a5, the mouse homologue of human CYP2A6, encodes for the enzyme responsible for the primary metabolism of nicotine.

出版机构:Springer Verlag

刊物名称:Psychopharmacology

出版时间:2006

ISSN:0033-3158

数据源:报刊文摘

Nicotine self-administration in mice is associated with rates of nicotine inactivation by CYP2A5

Rationale Cyp2a5, the mouse homologue of human CYP2A6, encodes for the enzyme responsible for the primary metabolism of nicotine.

出版机构:Springer Verlag

刊物名称:Psychopharmacology

出版时间:2006

ISSN:0033-3158

数据源:报刊文摘

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