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Correlation betweenin vitro andin vivo drug metabolism rate: Oxidation of ethoxybenzamide in rat

AbstractIn vitroand in vivocorrelations of the microsomal oxidation of drugs were examined, using ethoxybenzamide as a model drug. Ethoxybenzamide disappearance time course from rat plasma in vivowas analyzed by a two-compartment model assuming a Michaelis-Menten type elimination process.

出版机构:Springer US

刊物名称:Journal of Pharmacokinetics and Pharmacodynamics

出版时间:1978

ISSN:1567-567X

数据源:报刊文摘

Bromide oxidation and organic substitution in water treatment

During oxidative treatment of water with chlorine or ozone, the bromide present is oxidized to hypobromite. Oxidation to bromate, though thermodynamically possible, occurs with very low rates.

出版机构:Taylor & Francis

刊物名称:Journal of Environmental Science and Health, Part A- Toxic/Hazardous Substances & Environmental Engineering

出版时间:1978

ISSN:1093-4529

数据源:报刊文摘

Inhibition of epinephrine oxidation in weak alkaline solutions

The effect of sodium metabisulfite and cysteine on the oxidation of epinephrine in weak alkaline solutions was studied. The fluorescent intensity of the reacting mixture also was measured. Sodium metabisulfite in 2 ? 10?

出版机构:Wiley Subscription Services, Inc., A Wiley Company

刊物名称:Journal of Pharmaceutical Sciences

出版时间:1978

ISSN:0022-3549

数据源:报刊文摘

Effect of Ca++ and GABA on oxidation of glutamate and glutamine by rat brain synaptosomes

AbstractExperiments in vitro showed that the addition of Ca++ inhibits respiration of rat brain synaptosomes in the presence of glutamate and glutamine. The addition of GABA potentiates the inhibitory effect of Ca++ on the oxidation of glutamine but not of glutamate.

出版机构:Springer US

刊物名称:Bulletin of Experimental Biology and Medicine

出版时间:1978

ISSN:0007-4888

数据源:报刊文摘

Experimental effect of some hormones on the intensity of the free-radical lipid oxidation reaction

AbstractThe effect of adrenalin and hydrocortisone on free-radical oxidation of lipids in erythrocytes was investigated in experiments on rabbitsin vivo with modified lipid metabolism. Adrenalin in a dose of 0.

出版机构:Springer US

刊物名称:Bulletin of Experimental Biology and Medicine

出版时间:1978

ISSN:0007-4888

数据源:报刊文摘

The Importance and Use of Energy Transfer in the Liquid-Phase Chemiluminescence

Nonradiative electronic energy transfer (ET) is of great importance and of wide use in studies of chemiluminescence (CL) in solution. Some components of a chemiluminescent system, e. g. reactants, intermediates or products may serve as efficient energy acceptors.

出版机构:Taylor & Francis

刊物名称:Spectroscopy Letters

出版时间:1978

ISSN:0038-7010

数据源:报刊文摘

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