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Radical Cations in Aromatic Hydrocarbon Carcinogenesis

Most carcinogens, including polycyclic aromatic hydrocarbons (PAH), require metabolic activation to produce the ultimate electrophilic species that bind covalently with cellular macromolecules to trigger the cancer process.

出版机构:Informa Healthcare

刊物名称:Free Radical Research

出版时间:1990

ISSN:1071-5762

数据源:报刊文摘

Possible Roles of Free Radicals in Alcoholic Tissue Damage

Hepatic microsornes metabolize ethanol to a free radical metabolite which forms adducts with the spin trapping agents PBN (phenyl-N-t-butylnitrone) and DMPO (5,5-dimethyl-l-pyrroline N-oxide).

出版机构:Informa Healthcare

刊物名称:Free Radical Research

出版时间:1990

ISSN:1071-5762

数据源:报刊文摘

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