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5-Oxoproline accumulates in glutathione synthetase deficiency, an autossomic recessive inherited disorder clinically characterized by hemolytic anemia, metabolic acidosis, and severe neurological symptoms whose mechanisms are poorly known.
出版机构：Springer US 刊物名称：Metabolic Brain Disease 出版时间：2010 ISSN：0885-7490 数据源：报刊文摘
Electron spin resonance (ESR)-silent ascorbate solutions generate a detectable, likely concentration-dependent signal of ascorbyl free radicals (AFR) immediately upon addition of a molar excess of dimethyl sulfoxide (DMSO).
出版机构：Springer US 刊物名称：Neurochemical Research 出版时间：2010 ISSN：0364-3190 数据源：报刊文摘
We administered a controlled cortical impact (CCI) injury or sham injury to transgenic mice expressing either human APOE3 or APOE4 on a murine APOE-deficient background. RNA was prepared from the ipsilateral hippocampi and cortices retrieved at 24 h and 1 month post-TBI. 出版机构：Elsevier Science 刊物名称：Neuroscience 出版时间：2010 ISSN：0306-4522 数据源：报刊文摘
Glycation and oxidative stress are two important processes known to play a key role in complications of many disease processes. Oxidative stress, either via increasing reactive oxygen species (ROS), or by depleting the antioxidants may modulate the genesis of early glycated proteins in vivo. 出版机构：Elsevier Science 刊物名称：Pathogie Biologie 出版时间：2010 ISSN：0369-8114 数据源：报刊文摘
Cysteamine is a degradation product of the amino acid cysteine and a reduced form of cystamine. Cysteamine exhibits strong antioxidant activity and has been implicated in the treatment of neurodegenerative disorders such as Huntington's disease. 出版机构：Elsevier Science 刊物名称：Brain Research 出版时间：2010 ISSN：0006-8993 数据源：报刊文摘
Our group previously described increased reactive oxygen species (ROS) production within easily accessible peripheral blood mononuclear cells (PBMCs) in PD patients compared to healthy elderly subjects. 出版机构：Elsevier Science 刊物名称：Neuroscience Letters 出版时间：2010 ISSN：0304-3940 数据源：报刊文摘
Litters of rats were non-handled or handled (10 min/day, days 1?10 after birth). In adulthood they were subjected to a Morris water maze or used for biochemical evaluations. Female handled rats showed impairment in spatial learning. 出版机构：Springer US 刊物名称：Neurochemical Research 出版时间：2010 ISSN：0364-3190 数据源：报刊文摘
Symbiotic corals routinely experience hyperoxic conditions within their tissues due to the photosynthesis of the endosymbiotic dinoflagellate microalgae (Symbiodinium spp.). Symbiodinium spp. produce high intracellular levels of the osmolyte dimethylsulfoniopropionate (DMSP). 出版机构：Elsevier Science 刊物名称：Aquatic Toxicology 出版时间：2010 ISSN：0166-445X 数据源：报刊文摘
The present study investigates the allelopathic effects of Stratiotes aloides on the growth and antioxidative biomarkers of epiphytic and planktonic toxic cyanobacteria in a batch experiment over a 15-day exposure to different concentrations of aqueous acetone extract of this macrophyte. 出版机构：WILEY‐VCH Verlag 刊物名称：International Review of Hydrobiology 出版时间：2010 ISSN：1434-2944 数据源：报刊文摘
lthough it has been suggested that the renin?angiotensin (RA) system and cathepsins contribute to the development and vulnerability of atherosclerotic plaque, the interaction of the RA system and cathepsins is unclear. 出版机构：Elsevier Science 刊物名称：Atherosclerosis 出版时间：2010 ISSN：0021-9150 数据源：报刊文摘
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