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12-residue MST isolated from a marine organism is a potent serine protease inhibitor that has a double cyclic structure composed of two ester linkages formed between the ?-hydroxyl and ?-carboxyl groups, Thr3-Asp9 and Ser8-Asp11. 出版机构:John Wiley & Sons, Ltd. 刊物名称:Journal of Peptide Science 出版时间:2010 ISSN:1075-2617 数据源:报刊文摘
eries of oxazolidine-based compounds with a variety of substituents in positions 2 and 3 was synthesized and their stability studied. Ring opened intermediates formed on addition of limiting amounts of D2O to oxazolidine solutions, as observed by NMR. 出版机构:Wiley Subscription Services, Inc., A Wiley Company 刊物名称:Journal of Pharmaceutical Sciences 出版时间:2010 ISSN:0022-3549 数据源:报刊文摘
Termination of translation in eukaryotes is triggered by two polypeptide chain release factors, eukaryotic class?1 polypeptide chain release factor (eRF1) and eukaryotic class?2 polypeptide chain release factor?3. eRF1 is a three?domain protein that interacts with eukaryotic class? 出版机构:Blackwell Publishing Ltd 刊物名称:FEBS Journal 出版时间:2010 ISSN:1742-464X 数据源:报刊文摘
idine and quindoline derivatives linked to DNA stabilize duplex and quadruplex structuresOligonucleotide conjugates containing acridine and quindoline derivatives linked through a threoninol molecule were synthesized. 出版机构:Elsevier Science 刊物名称:Bioorganic & Medicinal Chemistry 出版时间:2010 ISSN:0968-0896 数据源:报刊文摘
eries of new 3-substituted isoxazolecarboxamides have been prepared from aldehydes. A key step was a 1,3-dipolar cycloaddition of nitrile oxides to ?,?-unsaturated esters. 出版机构:Bentham Science Publishers 刊物名称:Letters in Organic Chemistry 出版时间:2010 ISSN:1570-1786 数据源:报刊文摘
New highly cytotoxic 1?[5?organylsilyl(germyl)?2?furyl(thienyl)]nitroethenes (IC500.3?3 ?g ml?1) have been prepared by condensation reaction of corresponding silicon? and germanium?
出版机构:John Wiley & Sons, Ltd. 刊物名称:Applied Organometallic Chemistry 出版时间:2010 ISSN:0268-2605 数据源:报刊文摘
In an attempt to develop a low?k interlayer dielectric, adamantane?diphenyldiethynyl moiety containing oligomer is prepared. Oligomerization of 1,3,5,7?tetrakis[3/4?ethynylphenyl]adamantane (4) is accomplished by a Glaser?
出版机构:Wiley Subscription Services, Inc., A Wiley Company 刊物名称:Journal of Polymer Science Part A: Polymer Chemistry 出版时间:2006 ISSN:0887-624X 数据源:报刊文摘
In situ structural characterization of organic compounds attached to solid supports can be achieved by high-resolution magic angle spinning NMR (HRMAS NMR), a technique that provides solution-like spectra for resin-bound molecules. 出版机构:Bentham Science Publishers 刊物名称:Current Topics in Medicinal Chemistry 出版时间:2011 ISSN:1568-0266 数据源:报刊文摘
Out of options? Even though a systematic approach was chosen, which led to a set of four diastereomeric macrolides modeled around the proposed structure of leiodolide?B (see picture), the puzzle concerning the stereostructure of this cytotoxic metabolite derived from a deep? 出版机构:WILEY‐VCH Verlag 刊物名称:Angewandte Chemie International Edition 出版时间:2011 ISSN:1433-7851 数据源:报刊文摘
One of the practical applications of sugar-based crown ethers involves their use as chiral catalysts in enantioselective phase transfer reactions. 出版机构:Bentham Science Publishers 刊物名称:Letters in Organic Chemistry 出版时间:2010 ISSN:1570-1786 数据源:报刊文摘
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