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In hepatocytes, the accumulation of unfolded proteins in the endoplasmic reticulum (ER) causes ER stress and the unfolded protein response (UPR), mediated by the ER-resident stress sensors ATF-6, IRE1, and PERK. UPR-responsive genes are involved in the fate of ER-stressed cells. 出版机构：John Wiley & Sons, Ltd. 刊物名称：The Journal of Pathology 出版时间：2010 ISSN：0022-3417 数据源：报刊文摘
Ischemia was produced in rats by ligature of the left anterior descending coronary artery for 30min. At the end of the 2-h reperfusion, western blot analysis of the inflammatory and apoptotic markers tumor necrosis factor-? (TNF-? 出版机构：Elsevier Science 刊物名称：European Journal of Pharmacology 出版时间：2010 ISSN：0014-2999 数据源：报刊文摘
No Abstract 出版机构：WILEY‐VCH Verlag 刊物名称：Angewandte Chemie International Edition 出版时间：2010 ISSN：1433-7851 数据源：报刊文摘
Objective Systemic inflammatory mediators, including the high mobility group box 1 (HMGB1) protein, play important roles in the development of various inflammatory conditions.
出版机构：SP Birkhäuser Verlag Basel 刊物名称：Inflammation Research 出版时间：2010 ISSN：1023-3830 数据源：报刊文摘
Shift work schedule has been associated with several health problems, including deleterious effects on the cardiovascular system. 出版机构：Elsevier Science 刊物名称：Atherosclerosis 出版时间：2010 ISSN：0021-9150 数据源：报刊文摘
Mediterranean diet has been promoted as the preferred dietary model for cardiovascular disease prevention in the United States. 出版机构：Elsevier Science 刊物名称：Atherosclerosis 出版时间：2010 ISSN：0021-9150 数据源：报刊文摘
Inhalation is a non-invasive approach for both local and systemic drug delivery. This study aimed to define the therapeutic window for solid lipid nanoparticles (SLNs) as a drug delivery system by inhalation from a toxicological point of view. 出版机构：Elsevier Science 刊物名称：European Journal of Pharmaceutics and Biopharmaceutics 出版时间：2010 ISSN：0939-6411 数据源：报刊文摘
Macrophage presence within atherosclerotic plaque is a feature of instability and a risk factor for plaque rupture and clinical events. Activated macrophages express high levels of the translocator protein/peripheral benzodiazepine receptor (TSPO/PBR). 出版机构：Elsevier Science 刊物名称：Atherosclerosis 出版时间：2010 ISSN：0021-9150 数据源：报刊文摘
The preferred amino acids in the proteolytic sites have been considered to be similar between caspase-1 and caspase-9, which do not support their differential functions in inflammatory pyroptosis and apoptosis. We attempted to solve this problem. 出版机构：Elsevier Science 刊物名称：Atherosclerosis 出版时间：2010 ISSN：0021-9150 数据源：报刊文摘
Serine proteases form a large family of protein-cleaving enzymes that play an essential role in processes like blood coagulation, apoptosis and inflammation. 出版机构：Elsevier Science 刊物名称：Molecular Immunology 出版时间：2010 ISSN：0161-5890 数据源：报刊文摘
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