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Endothelium-dependent and -independent vasorelaxation induced by CIJ-3-2F, a novel benzyl-furoquinoline with antiarrhythmic action, in rat aorta

This study was designed to examine the mechanism of relaxation induced by CIJ-3-2F, a benzyl-furoquinoline antiarrhythmic agent, in rat thoracic aorta at the tissue and cellular levels.

出版机构:Elsevier Science

刊物名称:Life Sciences Including Pharmacology Letters

出版时间:2010

ISSN:0024-3205

数据源:报刊文摘

Chronic inhibition of farnesyl pyrophosphate synthase improves endothelial function in spontaneously hypertensive rats

Farnesyl pyrophosphate synthase (FPPS, EC 2.5.1.10), an essential enzyme in the mevalonate pathway, catalyzes the synthesis of isoprenoid intermediates.

出版机构:Elsevier Science

刊物名称:Biochemical Pharmacology

出版时间:2010

ISSN:0006-2952

数据源:报刊文摘

Nitric oxide production and blood corpuscle dynamics in response to the endocrine status of female rats

Menopause is associated with marked changes in the endocrine profile, and increases the risk of vascular disease. However, the effect of hormones on the vascular system is still unclear.

出版机构:Elsevier Science

刊物名称:Thrombosis Research

出版时间:2010

ISSN:0049-3848

数据源:报刊文摘

Extracellular alkalinization induces endothelium-derived nitric oxide dependent relaxation in rat thoracic aorta

To investigate the mechanism through which the extracellular alkalinization promotes relaxation in rat thoracic aorta.

出版机构:Elsevier Science

刊物名称:Nitric Oxide

出版时间:2010

ISSN:1089-8603

数据源:报刊文摘

Intracavernous Transplantation of Bone Marrow‐Derived Mesenchymal Stem Cells Restores Erectile Function of Streptozocin‐Induced Diabetic Rats

BSTRACT

Introduction. Erectile dysfunction (ED) is a frequent complication of diabetes mellitus. The efficacy of common ED therapies is low for diabetes associated ED.

Aim.

出版机构:Blackwell Publishing Inc

刊物名称:The Journal of Sexual Medicine

出版时间:2011

ISSN:1743-6095

数据源:报刊文摘

The relaxation responses to corticotropin-releasing factor in rat aorta are endothelium dependent and gestationally regulated

OBJECTIVE: Our purpose was to examine the hypothesis that the relaxant response to corticotropin-releasing factor is endothelium dependent and changes during pregnancy.

出版机构:Elsevier Science

刊物名称:American Journal of Obstetrics and Gynecology

出版时间:1997

ISSN:0002-9378

数据源:报刊文摘

LPS induces permeability injury in lung microvascular endothelium via AT1 receptor

Besides, increased rat pulmonary microvascular endothelial cell monolayer permeability coefficient (K f) was measured after treatment with LPS and/or Ang II, respectively. LPS/Ang II, treatment resulted in a significant increase in K f. Ang II cooperates with LPS to further increase K f.

出版机构:Elsevier Science

刊物名称:Archives of Biochemistry and Biophysics

出版时间:2005

ISSN:0003-9861

数据源:报刊文摘

Effects of natural free radical scavengers on peripheral nerve and neurovascular function in diabetic rats

SummaryIncreased generation of reactive oxygen species, coupled with impaired endogenous scavenging mechanisms, plays a prominent role in the aetiology of neurovascular abnormalities in experimental diabetes mellitus.

出版机构:Springer Verlag

刊物名称:Diabetologia

出版时间:1995

ISSN:0012-186X

数据源:报刊文摘

Interactions between essential fatty acid, prostanoid, polyol pathway and nitric oxide mechanisms in the neurovascular deficit of diabetic rats

SummaryImpaired -6 essential fatty acid metabolism and exaggerated polyol pathway flux contribute to the neurovascular abnormalities in streptozotocin-diabetic rats.

出版机构:Springer Verlag

刊物名称:Diabetologia

出版时间:1996

ISSN:0012-186X

数据源:报刊文摘

Pharmacological manipulation of vascular endothelium function in non-diabetic and streptozotocin-diabetic rats: effects on nerve conduction, hypoxic resistance and endoneurial capillarization

There were dose-dependent reductions in sciatic motor and saphenous sensory conduction velocity. The two inhibitors acted synergistically, thus, the 5–6% motor conduction deficits (p<0.

出版机构:Springer Verlag

刊物名称:Diabetologia

出版时间:1993

ISSN:0012-186X

数据源:报刊文摘