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Extracellular alkalinization induces endothelium-derived nitric oxide dependent relaxation in rat thoracic aorta

To investigate the mechanism through which the extracellular alkalinization promotes relaxation in rat thoracic aorta.

出版机构:Elsevier Science

刊物名称:Nitric Oxide

出版时间:2010

ISSN:1089-8603

数据源:报刊文摘

Identification of trace-amine-associated receptors (TAAR) in the rat aorta and their role in vasoconstriction by β-phenylethylamine

Trace amines including tyramine and �-phenylethylamine (�-PEA) increase blood pressure and cause vasoconstriction which is attributed to indirect sympathomimetic actions. However, there is evidence that they may also have non-sympathomimetic mechanisms.

出版机构:Springer Verlag

刊物名称:Naunyn-Schmiedeberg's Archives of Pharmacology

出版时间:2010

ISSN:0028-1298

数据源:报刊文摘

Cytochrome P450 Pathway Contributes to Methanandamide-induced Vasorelaxation in Rat Aorta

The cannabinoid methanandamide has vasodilatory properties linked to hyperpolarisation. The aim of the present work was to investigate the vasorelaxant effects of methanandamide in rat aorta, focusing on the role of cytochrome P450 pathway.

出版机构:Springer US

刊物名称:Cardiovascular Drugs and Therapy

出版时间:2010

ISSN:0920-3206

数据源:报刊文摘

The relaxation responses to corticotropin-releasing factor in rat aorta are endothelium dependent and gestationally regulated

OBJECTIVE: Our purpose was to examine the hypothesis that the relaxant response to corticotropin-releasing factor is endothelium dependent and changes during pregnancy.

出版机构:Elsevier Science

刊物名称:American Journal of Obstetrics and Gynecology

出版时间:1997

ISSN:0002-9378

数据源:报刊文摘

Lack of heterologous receptor desensitization induced by angiotensin II type 1 receptor activation in isolated normal rat thoracic aorta

We tested whether heterologous receptor desensitization induced by activation of AT1 receptors may explain the purported relaxation produced by angiotensin II in normal rat aorta. Also, the role for AT2 receptors in the promotion of vasodilation was studied.

出版机构:Elsevier Science

刊物名称:Vascular Pharmacology

出版时间:2011

ISSN:1537-1891

数据源:报刊文摘

Upregulation of Proteinase-Activated Receptor-2 and Increased Response to Trypsin in Endothelial Cells after Exposure to Oxidative Stress in Rat Aortas

Background/Aims: The effects of oxidative stress on the vascular responsiveness to the agonists of proteinase-activated receptors (PARs) were investigated. Methods: Serum-free incubation was utilized to impose oxidative stress to isolated rat aortas.

出版机构:S. Karger AG

刊物名称:Journal of Vascular Research

出版时间:2010

ISSN:1018-1172

数据源:报刊文摘

Effects of angiopeptin on transplant arteriosclerosis in the rat

AbstractThe influence of the somatostatin analogue angiopeptin on transplant arteriosclerosis was investigated using two aortic transplantation rat models.

出版机构:Blackwell Publishing Ltd

刊物名称:Transplant International

出版时间:1995

ISSN:0934-0874

数据源:报刊文摘

Aortic glycosaminoglycans in avitaminosis

AbstractIn hypovitaminosis K induced by a vitamin K-deficient diet or by Pelentan (ethyl biscoumacetate) a decrease was observed in the total content of glycosaminoglycans (GAG) and a change in the relative proportions of their fractions in the aortic wall of rats.

出版机构:Springer US

刊物名称:Bulletin of Experimental Biology and Medicine

出版时间:1979

ISSN:0007-4888

数据源:报刊文摘

His-Arg-Trp potently attenuates contracted tension of thoracic aorta of Sprague-Dawley rats through the suppression of extracellular Ca2+ influx

In the present study, we primarily attempted to identify di- and tri-peptides showing potent vasodilation in 1.0?M phenylephrine-contracted thoracic aortas of Sprague-Dawley rats.

出版机构:Elsevier Science

刊物名称:Peptides

出版时间:2009

ISSN:0196-9781

数据源:报刊文摘

Structure–activity relationship study on Tyr9 of urotensin-II(4–11): Identification of a partial agonist of the UT receptor

Urotensin-II (U-II) activates the U-II receptor (UT) to modulate a range of biological responses at both central and peripheral sites. Previous studies have demonstrated that the sequence Trp7-Lys8-Tyr9 of the cyclic portion of the peptide is crucial for biological activity.

出版机构:Elsevier Science

刊物名称:Peptides

出版时间:2009

ISSN:0196-9781

数据源:报刊文摘