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Excitation of rat spinal ventral horn neurons by purinergic P2X and P2Y receptor activation

TP?S, a nonhydrolyzable ATP analog, was found to dose-dependently generate an inward current at a holding potential of ?70mV (EC50 =43?M) in lamina IX neurons of rat spinal cord slices using the whole-cell patch-clamp technique. This inward current had an extrapolated reversal potential of ?

出版机构:Elsevier Science

刊物名称:Brain Research

出版时间:2010

ISSN:0006-8993

数据源:报刊文摘

Activation of astrocytes in the spinal cord contributes to the development of bilateral allodynia after peripheral nerve injury in rats

ivation of spinal cord microglia and astrocytes after peripheral nerve injury contributes to the development of behavioral hypersensitivity. Suppression of spinal cord glial activation attenuates the development of nerve injury-induced allodynia.

出版机构:Elsevier Science

刊物名称:Brain Research

出版时间:2010

ISSN:0006-8993

数据源:报刊文摘

Global gene expression profiling of somatic motor neuron populations with different vulnerability identify molecules and pathways of degeneration and protection

Different somatic motor neuron subpopulations show a differential vulnerability to degeneration in diseases such as amyotrophic lateral sclerosis, spinal muscular atrophy and spinobulbar muscular atrophy.

出版机构:Oxford University Press

刊物名称:Brain

出版时间:2010

ISSN:0006-8950

数据源:报刊文摘

Expression of Slit2 and Robo1 after traumatic lesions of the rat spinal cord

We have used semi-quantitative RT-PCR, Western blot, and immunofluorescence imaging approaches to detect the expression levels of Slit2 and its receptor Robo1 in the rat spinal cord after traumatic lesions.

出版机构:Elsevier Science

刊物名称:Acta Histochemica

出版时间:2011

ISSN:0065-1281

数据源:报刊文摘

Cerebrospinal Fluid Pressure Response to Upper Cervical Vertebral Motion and Displacement in the Anesthetized Rat

This study examined whether aligned or off-axis (subluxated) static and dynamic vertebral displacement within normal physiological ranges modulated cerebrospinal fluid pressure (CSF) as is considered to occur by some chiropractic theories.

出版机构:Elsevier Science

刊物名称:Journal of Manipulative and Physiological Therapeutics

出版时间:2010

ISSN:0161-4754

数据源:报刊文摘

Slope analysis of somatosensory evoked potentials in spinal cord injury for detecting contusion injury and focal demyelination

In spinal cord injury (SCI) research there is a need for reliable measures to determine the extent of injury and assess progress due to natural recovery, drug therapy, surgical intervention or rehabilitation.

出版机构:Elsevier Science

刊物名称:Journal of Clinical Neuroscience

出版时间:2010

ISSN:0967-5868

数据源:报刊文摘

Combination of olfactory ensheathing cells with local versus systemic cAMP treatment after a cervical rubrospinal tract injury

The failure of CNS axons to regenerate following traumatic injury is due in part to a growth-inhibitory environment in CNS as well as a weak intrinsic neuronal growth response.

出版机构:Wiley Subscription Services, Inc., A Wiley Company

刊物名称:Journal of Neuroscience Research

出版时间:2010

ISSN:0360-4012

数据源:报刊文摘

Neuroprotective effects of tamoxifen on experimental spinal cord injury in rats

The aim of this study was to evaluate the effects of tamoxifen on tumor necrosis factor ? (TNF-?) and interleukin 1? (IL-1?) levels and ultrastructural changes in rats with spinal cord injury.

出版机构:Elsevier Science

刊物名称:Journal of Clinical Neuroscience

出版时间:2010

ISSN:0967-5868

数据源:报刊文摘

Extensive scarring induced by chronic intrathecal tubing augmented cord tissue damage and worsened functional recovery after rat spinal cord injury

Intrathecal infusion has been widely used to directly deliver drugs or neurotrophins to a lesion site following spinal cord injury. Evidence shows that intrathecal infusion is efficient for 7 days but is markedly reduced after 14 days, due to time dependent occlusion.

出版机构:Elsevier Science

刊物名称:Journal of Neuroscience Methods

出版时间:2010

ISSN:0165-0270

数据源:报刊文摘

Localized 1H NMR spectroscopy of rat spinal cord in Vivo

A movable, actively decoupled surface coil has been employed to obtain a localized 1H NMR spectrum from the lumbosacral spinal cord of a live Lewis rat. A volume selective `VOSY? normally spelled out as `volume selective spectroscopy?

出版机构:Wiley Subscription Services, Inc., A Wiley Company

刊物名称:Magnetic Resonance in Medicine

出版时间:1996

ISSN:0740-3194

数据源:报刊文摘