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Administration of GABAB receptor positive allosteric modulators inhibit the expression of previously established methamphetamine-induced conditioned place preference

? Methamphetamine place preference is disrupted by GABAB receptor modulators. ? Memory maintenance is disrupted by augmenting endogenous GABA. ? GABAB receptor positive allosteric modulators may treat psychostimulant addiction.

出版机构:Elsevier Science

刊物名称:Behavioural Brain Research

出版时间:2011

ISSN:0166-4328

数据源:报刊文摘

Naloxone blocks ethanol-mediated appetitive conditioning and locomotor activation in adolescent rats

� Ethanol-induced appetitive second-order conditioning in adolescent rats. � Ethanol induced motor behavioral stimulation in adolescent rats. � Administration of naloxone inhibited the appetitive conditioning.� Naloxone dose-dependently blocked ethanol's motor activating effects.

出版机构:Elsevier Science

刊物名称:Behavioural Brain Research

出版时间:2011

ISSN:0166-4328

数据源:报刊文摘

Acute, post-ischemic sensorimotor deficits correlate positively with infarct size but fail to predict its occurrence and magnitude after middle cerebral artery occlusion in rats

� Middle cerebral artery occlusion induces neurological deficits (ND) in rats. � Does acute ND predict the occurrence and magnitude of brain infarct? � Acute ND correlates positively with striatal and cortical infarct size. � However, acute ND occurs also in the absence of brain infarct.

出版机构:Elsevier Science

刊物名称:Behavioural Brain Research

出版时间:2011

ISSN:0166-4328

数据源:报刊文摘

Riluzole rapidly attenuates hyperemotional responses in olfactory bulbectomized rats, an animal model of depression

? Single (1st day administration) and subchronic (7th day administration) riluzole treatment (1?10mg/kg, po) significantly and dose-dependently reduced hyperemotional responses in OBX rats. ?

出版机构:Elsevier Science

刊物名称:Behavioural Brain Research

出版时间:2011

ISSN:0166-4328

数据源:报刊文摘

Rat tibial osteotomy model providing a range of normal to impaired healing

The purpose of this study was to develop an inexpensive and easily implemented rat tibial osteotomy model capable of producing a range of healing outcomes. A saw blade was used to create a transverse osteotomy of the tibia in 89 Sprague?Dawley rats. A 0.89?

出版机构:Wiley Subscription Services, Inc., A Wiley Company

刊物名称:Journal of Orthopaedic Research

出版时间:2011

ISSN:0736-0266

数据源:报刊文摘

The Effect of timing of conversion from external fixation to secondary intramedullary nailing in experimental tibial fractures

Diaphyseal tibial fractures with initial temporary external fixation (EF) are usually converted to intramedullary nailing (IMN) within 2 weeks, and no consensus on the optimal conversion time point exists.

出版机构:Wiley Subscription Services, Inc., A Wiley Company

刊物名称:Journal of Orthopaedic Research

出版时间:2011

ISSN:0736-0266

数据源:报刊文摘

Chronic exposure to aluminum reduces tyrosine hydroxylase expression in the substantia nigra and locomotor performance in rats

? The present study evaluates by means of immunohistochemistry of tyrosine hydroxylase, the effects of chronic Al exposure in adulthood or since intra-uterine age on the dopaminergic neurons. ?

出版机构:Elsevier Science

刊物名称:Neuroscience Letters

出版时间:2011

ISSN:0304-3940

数据源:报刊文摘

Expression of apoptosis-inducing factor (AIF) in the aged rat brain

The mitochondrial flavoprotein apoptosis-inducing factor (AIF) promotes cell death upon nuclear translocation or by impinging on mitochondrial respiratory complex-I activity.

出版机构:Elsevier Science

刊物名称:Neurobiology of Aging

出版时间:2011

ISSN:0197-4580

数据源:报刊文摘

Anti-oxidative effects of d-allose, a rare sugar, on ischemia-reperfusion damage following focal cerebral ischemia in rat

? Brain damage after transient ischemia was decreased by d-allose administration. ? Oxidative stress markers were also reduced by d-allose. ?d-allose has anti-oxidative effects and induces neuroprotection in cerbral ischemia.

出版机构:Elsevier Science

刊物名称:Neuroscience Letters

出版时间:2011

ISSN:0304-3940

数据源:报刊文摘

Perinatal exposure to parasiticide ivermectin: long-term effects on reproductive parameters of adult male rats

Ivermectin is one of the most widely used antiparasitic drugs globally. The aim of this study was to evaluate the chronic effects of perinatal exposure to ivermectin on male reproductive parameters in rats. Pregnant rats were treated daily by oral gavage with 0.4 or 1.

出版机构:Taylor & Francis

刊物名称:Toxicological and Environmental Chemistry

出版时间:2011

ISSN:0277-2248

数据源:报刊文摘