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Hyperpolarization-activated ion channels as targets for nitric oxide signalling in deep cerebellar nuclei

Abstract

Most biological effects of nitric oxide (NO) in the brain are mediated by guanylyl cyclase-coupled NO receptors, whose activation results in increased intracellular cGMP levels.

出版机构:Blackwell Publishing Ltd

刊物名称:European Journal of Neuroscience

出版时间:2010

ISSN:0953-816X

数据源:报刊文摘

Scanning laser cytometry: alterations induced by cholestatic agents in isolated rat hepatocyte couplets

AbstractScanning laser cytometry, an analytic technique that provides an accurate fluorescent measurement in adherent cells, was used to study cholestatic mechanisms in isolated rat hepatocyte couplets (IRHC).

出版机构:Springer Netherlands

刊物名称:Cell Biology and Toxicology

出版时间:1994

ISSN:0742-2091

数据源:报刊文摘

The histaminergic tuberomammillary nucleus is critical for motivated arousal

Abstract

Obtaining food, shelter or water, or finding a mating partner are examples of motivated behaviors, which are essential to preserve the species.

出版机构:Blackwell Publishing Ltd

刊物名称:European Journal of Neuroscience

出版时间:2010

ISSN:0953-816X

数据源:报刊文摘

Protective effect of hydrogen sulfide on hypoxic respiratory suppression in medullary slice of neonatal rats

Hydrogen sulfide (H2S) has been shown to play a protective role in injury of cells induced by hypoxia. Little is known however about its effect on medullary hypoxia-induced rhythmic respiratory suppression.

出版机构:Elsevier Science

刊物名称:Respiratory Physiology & Neurobiology

出版时间:2010

ISSN:1569-9048

数据源:报刊文摘

Evolution of the percutaneous penetration and distribution of uranyl nitrate as a function of skin-barrier integrity: an in vitro assessment

ecommended by OECD Guidelines, percutaneous penetration studies consider intact skin, but rarely injured skin. Recent years have witnessed a growing concern for these two types of dermal exposure in the industry, particularly in the nuclear industry.

出版机构:Informa Healthcare

刊物名称:Drug Chem Toxicol

出版时间:2010

ISSN:0148-0545

数据源:报刊文摘

Presence and vascular pharmacology of KATP channel subtypes in rat central and peripheral tissues

KATP channel openers are vasodilators and induce headache in normal subjects. We previously identified the Kir6.1/SUR2B KATP channel subtype in major cerebral and dural arteries of rat, pig and man. We hypothesized that craniovascular Kir6.

出版机构:Elsevier Science

刊物名称:European Journal of Pharmacology

出版时间:2010

ISSN:0014-2999

数据源:报刊文摘

Fructose-1,6-diphosphate inhibits seizure acquisition in fast hippocampal kindling

Inhibition of glycolytic metabolism may provide a new therapy for refractory epilepsy. Fructose-1,6-diphosphate (FDP), which inhibits glycolysis and diverts glucose into the pentose phosphate pathway, has strong inhibitory action on seizures induced by chemical convulsants.

出版机构:Elsevier Science

刊物名称:Neuroscience Letters

出版时间:2010

ISSN:0304-3940

数据源:报刊文摘

Plasmid DNA transfection into fibroblasts of athymic rats

Without Abstract

出版机构:Springer US

刊物名称:Bulletin of Experimental Biology and Medicine

出版时间:1992

ISSN:0007-4888

数据源:报刊文摘

Activation of central CRF receptor 1 by cortagine results in enhanced passive coping with a naturalistic threat in mice

CRF receptor subtype 1 (CRF1), abundantly expressed in the central nervous system, has been implicated in defensive behavior in rodents. Pharmacological activation of CRF1 by peptidic agonists results in enhancement of anxiety-like behavior.

出版机构:Elsevier Science

刊物名称:Psychoneuroendocrinology

出版时间:2010

ISSN:0306-4530

数据源:报刊文摘

Enhanced c-Fos expression in superior colliculus, paraventricular thalamus and septum during learning of cue-reward association

Reward-mediated associative learning is important for recognizing the significance of environmental cues. Such learning involves convergence of multimodal sensory inputs with circuits involved in affective and memory processes.

出版机构:Elsevier Science

刊物名称:Neuroscience

出版时间:2010

ISSN:0306-4522

数据源:报刊文摘