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Oxygen-Linked Hydrogen Ion Binding of Human Hemoglobin. Effects of Carbon Dioxide and 2,3-Diphosphoglycerate I. Studies on Erythrolysate

id-base titrations were performed on oxygenated and deoxygenated erythrolysates at constant PCO2. The Haldane coefficient, - (?Hb-bound H+)/(?Hb-bound O2), was determined as a function of pH and PCO2 for various concentrations of 2,3-diphosphoglycerate (DPG).

出版机构:Informa Healthcare

刊物名称:Scandinavian Journal of Clinical and Laboratory Investigation

出版时间:1971

ISSN:0036-5513

数据源:报刊文摘

Oxygen-Linked Hydrogen Ion Binding of Human Hemoglobin. Effects of Carbon Dioxide and 2,3 - Diphosphoglycerate. II. Studies on Whole Blood

id-base titrations were performed on oxygenated and deoxygenated blood at constant PCO2. The BE-coefficient, - (?Blood-base excess)/(?Hb-bound O2), is 0.3 mol/mol for normal blood, varying between 0 and 0.4 with variations in pH, PCO2, and 2,3-diphosphoglycerate concentration.

出版机构:Informa Healthcare

刊物名称:Scandinavian Journal of Clinical and Laboratory Investigation

出版时间:1971

ISSN:0036-5513

数据源:报刊文摘

Affinity of Human Hemoglobin a to 2,3—Diphosphoglycerate. Effect of Hemoglobin Concentration and of pH

The affinity of human oxy- and deoxyhemoglobin A for 2,3-diphosphoglycerate was measured in purified hemoglobin solutions at 37 ?C and with near-physiological ionic composition.

出版机构:Informa Healthcare

刊物名称:Scandinavian Journal of Clinical and Laboratory Investigation

出版时间:1971

ISSN:0036-5513

数据源:报刊文摘

2, 3-Diphosphoglycerate and Creatine in the Red Cell during Human Pregnancy

The intraerythrocytic level of 2, 3-diphosphoglycerate is found to increase by about 30% during human pregnancy. Immediately after delivery, the 2, 3-DPG level decreases, and the concentration of inorganic phosphate in the plasma increases.

出版机构:Informa Healthcare

刊物名称:Scandinavian Journal of Clinical and Laboratory Investigation

出版时间:1971

ISSN:0036-5513

数据源:报刊文摘

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