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Interaction between Human or Dog Leucocyte Proteases and Plasma Protease Inhibitors

Neutral human and dog leucocyte proteases were inactivated by complexation with ?1-antitrypsin and with the ?-macroglobulins. These two inhibitors closely resemble one another in their affinity for the above-mentioned proteases and for chymotrypsin, but differ in their affinity for trypsin.

出版机构:Informa Healthcare

刊物名称:Scandinavian Journal of Clinical and Laboratory Investigation

出版时间:1971

ISSN:0036-5513

数据源:报刊文摘

In Vivo Interaction between α-Chymotrypsin and Plasma Proteins in the Dog

Minute amounts of bovine 125I-?-chymotrypsin injected intravenously into the dog were bound to the ?1-antitrypsin (about 85 per cent) and the a-macroglobulins (about 15 per cent). Injection of larger amounts resulted in a fall of the concentration of the ?-macroglobulins. Chymotrypsin-?

出版机构:Informa Healthcare

刊物名称:Scandinavian Journal of Clinical and Laboratory Investigation

出版时间:1971

ISSN:0036-5513

数据源:报刊文摘

Interactions between Bovine α-Chymotrypsin and the Protease Inhibitors of Human and Dog Serum in Vitro

With due allowance for the concentration of the inhibitors in serum bovine ?-chymotrypsin showed a greater relative affinity for ?1-antitrypsin or a lower affinity for ?2-macroglobulin than bovine trypsin. No complexation could be demonstrated between human ?

出版机构:Informa Healthcare

刊物名称:Scandinavian Journal of Clinical and Laboratory Investigation

出版时间:1971

ISSN:0036-5513

数据源:报刊文摘

Interactions in Vitro and in Vivo between Dog Trypsin and Dog Plasma Protease Inhibitors

Trace amounts of dog trypsin mixed with dog serum or injected i.v. into the dog were bound mainly to the a-macroglobulins (82 per cent) and to ?1-antitrypsin (18 per cent). The relative affinity of dog trypsin for the ?

出版机构:Informa Healthcare

刊物名称:Scandinavian Journal of Clinical and Laboratory Investigation

出版时间:1971

ISSN:0036-5513

数据源:报刊文摘

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