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Thrombin-Induced Vasoconstriction in the Pulmonary Circulation

Supernatants from thrombin-treated cell suspensions acted as vasoconstrictors on isolated perfused dog lung lobes. The vasoconstriction was due to serotonin released from the platelets. Thrombin caused an increase of pulmonary vascular resistance in vivo.

出版机构:Informa Healthcare

刊物名称:Scandinavian Journal of Clinical and Laboratory Investigation

出版时间:1971

ISSN:0036-5513

数据源:报刊文摘

Studies on Soluble Fibrin in Plasma I. N-Terminal Analysis of a Modified Fraction I (Cohn) from Normal and Thrombin-Incubated Plasma

Purified fibrinogen and fibrin, and the clottable proteins of normal plasma, have been examined by quantitative N-terminal amino acid analysis. When normal plasma was incubated with traces of thrombin, the clottable proteins always contained N-terminal glycine.

出版机构:Informa Healthcare

刊物名称:Scandinavian Journal of Clinical and Laboratory Investigation

出版时间:1971

ISSN:0036-5513

数据源:报刊文摘

Hemodynamic Changes of Adenosine Diphosphate, Adenosine Triphosphate, and Thrombin in Relation to Their Platelet-Aggregating Activity

DP and ATP were infused into the systemic and pulmonary circulation of dogs. Thrombin was infused into the pulmonary circulation. All the agents caused a decreased platelet count. ADP and ATP caused an increase in cardiac output.

出版机构:Informa Healthcare

刊物名称:Scandinavian Journal of Clinical and Laboratory Investigation

出版时间:1971

ISSN:0036-5513

数据源:报刊文摘

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